| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
|---|
| Ligand | BDBM349478 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Competitive Radioligand Binding Assay 2 |
|---|
| Ki | 1.80±n/a nM |
|---|
| Citation |  Rishton, GM; Catalano, SM; Look, GC Isoindoline compositions and methods for treating neurodegenerative disease US Patent US10207991 Publication Date 2/19/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sigma intracellular receptor 2 |
|---|
| Name: | Sigma intracellular receptor 2 |
|---|
| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 20857.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q5BJF2 |
|---|
| Residue: | 176 |
|---|
| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
|
|
|
|---|
| BDBM349478 |
|---|
| n/a |
|---|
| Name | BDBM349478 |
|---|
| Synonyms: | US10207991, Ex. Cpd. No. 19 | US10611728, Example Compound 19 | US11691947, Example 19 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H21Cl2N |
|---|
| Mol. Mass. | 370.315 |
|---|
| SMILES | CC(CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc3ccccc3c2C1 |
|---|
| Structure | 
|
|---|
Search and Browse
