| Reaction Details |
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 | Report a problem with these data |
| Target | N-acetyltransferase Eis |
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| Ligand | BDBM349605 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Eis inhibition assay |
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| IC50 | 300±n/a nM |
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| Citation |  Garneau-Tsodikova, S; Tsodikov, OV; Posey, JE Eis inhibitors US Patent US10208000 Publication Date 2/19/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| N-acetyltransferase Eis |
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| Name: | N-acetyltransferase Eis |
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| Synonyms: | Aminoglycoside N-acetyltransferase | EIS_MYCTU | Enhanced intracellular survival protein | N-acetyltransferase Eis | Protein-lysine N-acetyltransferase | eis |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43803.37 |
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| Organism: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
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| Description: | ChEMBL_116995 |
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| Residue: | 402 |
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| Sequence: | MTVTLCSPTEDDWPGMFLLAAASFTDFIGPESATAWRTLVPTDGAVVVRDGAGPGSEVVG
MALYMDLRLTVPGEVVLPTAGLSFVAVAPTHRRRGLLRAMCAELHRRIADSGYPVAALHA
SEGGIYGRFGYGPATTLHELTVDRRFARFHADAPGGGLGGSSVRLVRPTEHRGEFEAIYE
RWRQQVPGGLLRPQVLWDELLAECKAAPGGDRESFALLHPDGYALYRVDRTDLKLARVSE
LRAVTADAHCALWRALIGLDSMERISIITHPQDPLPHLLTDTRLARTTWRQDGLWLRIMN
VPAALEARGYAHEVGEFSTVLEVSDGGRFALKIGDGRARCTPTDAAAEIEMDRDVLGSLY
LGAHRASTLAAANRLRTKDSQLLRRLDAAFASDVPVQTAFEF
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| BDBM349605 |
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| n/a |
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| Name | BDBM349605 |
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| Synonyms: | US10208000, Compound 47 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17N3O5S |
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| Mol. Mass. | 411.431 |
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| SMILES | COc1cc(cc2ccccc12)N(C)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 |
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| Structure | 
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