| Reaction Details |
|---|
 | Report a problem with these data |
| Target | POU domain, class 2, transcription factor 2 |
|---|
| Ligand | BDBM350833 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | 10000±n/a nM |
|---|
| Citation |  Bacon, EM; Cai, ZR; Cottell, JJ; Ji, M; Jin, H; Lazerwith, SE; Morganelli, PA; Pyun, H Polycyclic-carbamoylpyridone compounds and their pharmaceutical use US Patent US9795602 Publication Date 10/24/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| POU domain, class 2, transcription factor 2 |
|---|
| Name: | POU domain, class 2, transcription factor 2 |
|---|
| Synonyms: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 | OCT2 | OCT2 | OTF-2 | OTF2 | Oct-2 | Octamer-binding protein 2 | Octamer-binding transcription factor 2 | Octamer-binding transcription factor 2 (OCT2) | PO2F2_HUMAN | POU domain, class 2, transcription factor 2 | POU2F2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 51217.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_109671 |
|---|
| Residue: | 479 |
|---|
| Sequence: | MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQNPQNKTSPFSVSPTGPS
TKIKAEDPSGDSAPAAPLPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHL
QPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLS
HPQPPKCLEPPSHPEEPSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTT
ISRFEALNLSFKNMCKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKK
RTSIETNVRFALEKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSA
APMLPSPGKPASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGG
GGGGAAPPLNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGPGLWWNPAPYQP
|
|
|
|---|
| BDBM350833 |
|---|
| n/a |
|---|
| Name | BDBM350833 |
|---|
| Synonyms: | US9795602, Compound 39 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H20ClF2N3O5 |
|---|
| Mol. Mass. | 467.85 |
|---|
| SMILES | CCN1[C@@H]2COCC[C@@H]2n2cc(C(=O)NCc3ccc(F)c(Cl)c3F)c(=O)c(O)c2C1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
