| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 [C299A] |
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| Ligand | BDBM16419 |
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| Substrate/Competitor | BDBM16418 |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| Ki | 303000±n/a nM |
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| Citation |  Brownlee, JM; Carlson, E; Milne, AC; Pape, E; Harrison, DH Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes. Bioorg Chem34:424-44 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Aldo-keto reductase family 1 member B1 [C299A] |
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| Name: | Aldo-keto reductase family 1 member B1 [C299A] |
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| Synonyms: | AKR1B1 | ALDR1 | ALDR_HUMAN | ALR2 | AR | Aldose Reductase (ALR2) Mutant (C299A) |
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| Type: | Enzyme |
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| Mol. Mass.: | 35823.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15121[C299A] |
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| Residue: | 316 |
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| Sequence: | MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ
EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK
EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP
AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK
HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVAA
LLSCTSHKDYPFHEEF
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| BDBM16419 |
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| BDBM16418 |
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| Name | BDBM16419 |
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| Synonyms: | 2-phenylacetic acid | Benzeneacetic acid | CHEMBL1044 | Phenylacetate, XIX | Phenylacetic acid | phenylacetate |
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| Type | Small organic molecule |
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| Emp. Form. | C8H8O2 |
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| Mol. Mass. | 136.1479 |
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| SMILES | OC(=O)Cc1ccccc1 |
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| Structure | 
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