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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Ligand | BDBM165925 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | The [3H]-methyllycaconitine binding assay | ||
| Ki | 1.60±n/a nM | ||
| Citation |  Luithle, J; Böβ, F; Erb, C; Hafner, F; Schnizler, K; Flessner, T; Van Kampen, M; Van Der Staay, F 2-heteroaryl carboxamides US Patent US10214524 Publication Date 2/26/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuronal acetylcholine receptor subunit alpha-7 | |||
| Name: | Neuronal acetylcholine receptor subunit alpha-7 | ||
| Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 56502.44 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | Q05941 | ||
| Residue: | 502 | ||
| Sequence: |
| ||
| BDBM165925 | |||
| n/a | |||
| Name | BDBM165925 | ||
| Synonyms: | US10214524, Example 20 | US9067931, 20 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H24N2O2S | ||
| Mol. Mass. | 392.514 | ||
| SMILES | OCc1ccc(cc1)-c1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2 |r,wU:20.22,(7.63,-4,;6.09,-4,;5.32,-2.67,;3.78,-2.67,;3.01,-1.33,;3.78,,;5.32,,;6.09,-1.33,;3.01,1.33,;3.78,2.67,;3.01,4,;1.47,4,;.7,2.67,;-.8,2.35,;-.96,.82,;.44,.19,;1.47,1.33,;-2.3,.05,;-2.3,-1.49,;-3.63,.82,;-4.97,.05,;-4.97,-1.49,;-6.3,-2.26,;-7.63,-1.49,;-7.63,.05,;-6.3,.82,;-5.53,-.52,;-7.07,-.93,)| | ||
| Structure | 
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