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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase BTK | ||
| Ligand | BDBM359860 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Inhibition Assay | ||
| Ki | <100±n/a nM | ||
| Citation |  Laurent, A; Rose, Y Protein kinase inhibitors US Patent US9822120 Publication Date 11/21/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase BTK | |||
| Name: | Tyrosine-protein kinase BTK | ||
| Synonyms: | AGMX1 | ATK | Agammaglobulinaemia tyrosine kinase | Agammaglobulinemia tyrosine kinase | B cell progenitor kinase | B-cell progenitor kinase | BPK | BTK | BTK_HUMAN | Bruton tyrosine kinase | Tyrosine Kinase BTK | Tyrosine-protein kinase (BTK) | Tyrosine-protein kinase BTK (BTK) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 76289.95 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q06187 | ||
| Residue: | 659 | ||
| Sequence: |
| ||
| BDBM359860 | |||
| n/a | |||
| Name | BDBM359860 | ||
| Synonyms: | US9822120, Compound 14 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H26FN5O4S | ||
| Mol. Mass. | 547.601 | ||
| SMILES | Cc1ncc(COc2cc(F)cc(Oc3ccc(cc3)-c3nc(C4CC(O)(CO)C4)n4ccnc(N)c34)c2)s1 |(6.49,-1.11,;6.49,.43,;7.74,1.34,;7.26,2.8,;5.72,2.8,;4.63,3.89,;3.14,3.49,;2.05,4.58,;2.45,6.07,;1.36,7.16,;1.76,8.65,;-.12,6.76,;-.52,5.27,;-2.01,4.87,;-2.41,3.39,;-1.32,2.3,;-1.72,.81,;-3.21,.41,;-4.29,1.5,;-3.9,2.99,;-3.6,-1.08,;-2.7,-2.32,;-3.6,-3.57,;-3.21,-5.06,;-3.98,-6.39,;-2.64,-7.16,;-3.04,-8.65,;-1.1,-7.16,;-.33,-8.49,;-1.87,-5.83,;-5.07,-3.09,;-6.4,-3.86,;-7.74,-3.09,;-7.74,-1.55,;-6.4,-.78,;-6.4,.76,;-5.07,-1.55,;.57,4.18,;5.24,1.34,)| | ||
| Structure | 
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