| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytosolic arginine sensor for mTORC1 subunit 1 |
|---|
| Ligand | BDBM315516 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| IC50 | <10±n/a nM |
|---|
| Citation |  Ren, P; Liu, Y; Li, L; Chan, K; Wilson, TE Kinase inhibitors and methods of use US Patent US9828378 Publication Date 11/28/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytosolic arginine sensor for mTORC1 subunit 1 |
|---|
| Name: | Cytosolic arginine sensor for mTORC1 subunit 1 |
|---|
| Synonyms: | CAST1_HUMAN | CASTOR1 | Cellular arginine sensor for mTORC1 protein 1 | GATS-like protein 3 | GATSL3 | mTORC1 protein 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 36264.36 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8WTX7 |
|---|
| Residue: | 329 |
|---|
| Sequence: | MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGF
KELPPSEFLQVAEATWLVLNVSSHSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQT
DFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPRTQHGPSPTVHPIQSP
QNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIV
MDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYIST
FNFDHALVPEDGIGSVIEVLQRRQEGLAS
|
|
|
|---|
| BDBM315516 |
|---|
| n/a |
|---|
| Name | BDBM315516 |
|---|
| Synonyms: | US10172858, Table 2.12 | US9828378, # 12 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18N6O |
|---|
| Mol. Mass. | 334.3751 |
|---|
| SMILES | Nc1ncnc2n(nc(-c3cc4cc(O)ccc4[nH]3)c12)C1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
