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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | ||
| Ligand | BDBM315557 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| IC50 | >500±n/a nM | ||
| Citation |  Ren, P; Liu, Y; Li, L; Chan, K; Wilson, TE Kinase inhibitors and methods of use US Patent US9828378 Publication Date 11/28/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | |||
| Name: | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | ||
| Synonyms: | C2-PI3K | P3C2B_HUMAN | PI3K-C2beta | PIK3C2B | Phosphatidylinositol 4-phosphate 3-kinase C2 beta (PIK3C2B) | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide | Phosphoinositide 3-Kinase (PI3K), C2beta | Phosphoinositide 3-Kinase-C2-beta | PtdIns-3-kinase C2 beta | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 184784.86 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00750 | ||
| Residue: | 1634 | ||
| Sequence: |
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| BDBM315557 | |||
| n/a | |||
| Name | BDBM315557 | ||
| Synonyms: | US10172858, Table 2.54 | US9828378, # 54 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H16N6O2 | ||
| Mol. Mass. | 336.3479 | ||
| SMILES | Nc1ncnc2n(nc(-c3cc4cc(O)ccc4[nH]3)c12)C1CC(O)C1 |(-2.24,1.62,;-2.24,.08,;-3.57,-.69,;-3.57,-2.23,;-2.24,-3,;-.9,-2.23,;.56,-2.71,;1.47,-1.46,;.56,-.22,;.96,1.27,;.06,2.52,;.96,3.76,;.64,5.27,;1.79,6.3,;1.39,7.79,;3.25,5.82,;3.57,4.32,;2.43,3.29,;2.43,1.75,;-.9,-.69,;.96,-4.2,;.19,-5.53,;1.52,-6.3,;1.92,-7.79,;2.29,-4.97,)| | ||
| Structure | 
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