Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cytosolic arginine sensor for mTORC1 subunit 1 | ||
| Ligand | BDBM315560 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| IC50 | <25±n/a nM | ||
| Citation |  Ren, P; Liu, Y; Li, L; Chan, K; Wilson, TE Kinase inhibitors and methods of use US Patent US9828378 Publication Date 11/28/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cytosolic arginine sensor for mTORC1 subunit 1 | |||
| Name: | Cytosolic arginine sensor for mTORC1 subunit 1 | ||
| Synonyms: | CAST1_HUMAN | CASTOR1 | Cellular arginine sensor for mTORC1 protein 1 | GATS-like protein 3 | GATSL3 | mTORC1 protein 1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 36264.36 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q8WTX7 | ||
| Residue: | 329 | ||
| Sequence: |
| ||
| BDBM315560 | |||
| n/a | |||
| Name | BDBM315560 | ||
| Synonyms: | US10172858, Table 2.57 | US9828378, # 57 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H27N7O2 | ||
| Mol. Mass. | 433.5062 | ||
| SMILES | Nc1ncnc2n(nc(-c3cc4cc(O)ccc4[nH]3)c12)C1CCC(CC1)N1CCOCC1 |w:23.30,(-2.24,3.7,;-2.24,2.16,;-3.57,1.39,;-3.57,-.15,;-2.24,-.92,;-.9,-.15,;.56,-.63,;1.47,.62,;.56,1.86,;.96,3.35,;.06,4.6,;.96,5.84,;.64,7.35,;1.79,8.38,;1.39,9.87,;3.25,7.9,;3.57,6.4,;2.43,5.37,;2.43,3.83,;-.9,1.39,;.56,-2.17,;-.77,-2.94,;-.77,-4.48,;.56,-5.25,;1.9,-4.48,;1.9,-2.94,;.56,-6.79,;-.77,-7.56,;-.77,-9.1,;.56,-9.87,;1.9,-9.1,;1.9,-7.56,)| | ||
| Structure | 
| ||