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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cytosolic arginine sensor for mTORC1 subunit 1 | ||
| Ligand | BDBM315561 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| IC50 | >500±n/a nM | ||
| Citation |  Ren, P; Liu, Y; Li, L; Chan, K; Wilson, TE Kinase inhibitors and methods of use US Patent US9828378 Publication Date 11/28/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cytosolic arginine sensor for mTORC1 subunit 1 | |||
| Name: | Cytosolic arginine sensor for mTORC1 subunit 1 | ||
| Synonyms: | CAST1_HUMAN | CASTOR1 | Cellular arginine sensor for mTORC1 protein 1 | GATS-like protein 3 | GATSL3 | mTORC1 protein 1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 36264.36 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q8WTX7 | ||
| Residue: | 329 | ||
| Sequence: |
| ||
| BDBM315561 | |||
| n/a | |||
| Name | BDBM315561 | ||
| Synonyms: | US10172858, Table 2.58 | US9828378, # 58 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H30N8O | ||
| Mol. Mass. | 446.548 | ||
| SMILES | CN1CCN(CC1)C1CCC(CC1)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12 |w:7.7,(.56,-10.64,;.56,-9.1,;-.77,-8.33,;-.77,-6.79,;.56,-6.02,;1.9,-6.79,;1.9,-8.33,;.56,-4.48,;-.77,-3.71,;-.77,-2.17,;.56,-1.4,;1.9,-2.17,;1.9,-3.71,;.56,.14,;1.47,1.39,;.56,2.63,;.96,4.12,;.06,5.37,;.96,6.61,;.64,8.12,;1.79,9.15,;1.39,10.64,;3.25,8.67,;3.57,7.17,;2.43,6.14,;2.43,4.6,;-.9,2.16,;-2.24,2.93,;-2.24,4.47,;-3.57,2.16,;-3.57,.62,;-2.24,-.15,;-.9,.62,)| | ||
| Structure | 
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