Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | ||
Ligand | BDBM315561 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
IC50 | >500±n/a nM | ||
Citation | Ren, P; Liu, Y; Li, L; Chan, K; Wilson, TE Kinase inhibitors and methods of use US Patent US9828378 Publication Date 11/28/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | |||
Name: | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | ||
Synonyms: | C2-PI3K | P3C2B_HUMAN | PI3K-C2beta | PIK3C2B | Phosphatidylinositol 4-phosphate 3-kinase C2 beta (PIK3C2B) | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide | Phosphoinositide 3-Kinase (PI3K), C2beta | Phosphoinositide 3-Kinase-C2-beta | PtdIns-3-kinase C2 beta | ||
Type: | Enzyme | ||
Mol. Mass.: | 184784.86 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O00750 | ||
Residue: | 1634 | ||
Sequence: |
| ||
BDBM315561 | |||
n/a | |||
Name | BDBM315561 | ||
Synonyms: | US10172858, Table 2.58 | US9828378, # 58 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H30N8O | ||
Mol. Mass. | 446.548 | ||
SMILES | CN1CCN(CC1)C1CCC(CC1)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12 |w:7.7,(.56,-10.64,;.56,-9.1,;-.77,-8.33,;-.77,-6.79,;.56,-6.02,;1.9,-6.79,;1.9,-8.33,;.56,-4.48,;-.77,-3.71,;-.77,-2.17,;.56,-1.4,;1.9,-2.17,;1.9,-3.71,;.56,.14,;1.47,1.39,;.56,2.63,;.96,4.12,;.06,5.37,;.96,6.61,;.64,8.12,;1.79,9.15,;1.39,10.64,;3.25,8.67,;3.57,7.17,;2.43,6.14,;2.43,4.6,;-.9,2.16,;-2.24,2.93,;-2.24,4.47,;-3.57,2.16,;-3.57,.62,;-2.24,-.15,;-.9,.62,)| | ||
Structure |