| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid type B receptor subunit 2 |
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| Ligand | BDBM360732 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | GTPgS Binding Assay |
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| EC50 | 760±n/a nM |
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| Citation |  Faghih, R; Moeller, A; Ochse, M; Pohlki, F; Schmidt, M; Sippy, K; Turner, S; Van Der Kam, EL Substituted pyrazolopyrimidines and method of use US Patent US9828381 Publication Date 11/28/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid type B receptor subunit 2 |
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| Name: | Gamma-aminobutyric acid type B receptor subunit 2 |
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| Synonyms: | GABA B receptor | GABR2_RAT | Gabbr2 | Gpr51 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 105775.46 |
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| Organism: | Rattus norvegicus |
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| Description: | O88871 |
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| Residue: | 940 |
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| Sequence: | MASPPSSGQPRPPPPPPPPARLLLPLLLSLLLWLAPGAWGWTRGAPRPPPSSPPLSIMGL
MPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAI
KYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNA
VNPAILKLLKHFRWRRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVK
KLKGNDVRIILGQFDQNMAAKVFCCAFEESMFGSKYQWIIPGWYEPAWWEQVHVEANSSR
CLRRSLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQFEREYNSKRSGVGPSKFHGYAYDG
IWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGKIILNAMNETNFFGVTGQVVFRNGE
RMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPL
YSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDG
SFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIV
GGMLLIDLCILICWQAVDPLRRTVERYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVY
AYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQF
CIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVN
QASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILSLG
NFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHH
AYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
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| BDBM360732 |
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| n/a |
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| Name | BDBM360732 |
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| Synonyms: | US9828381, 8-17 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21F5N4 |
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| Mol. Mass. | 424.4103 |
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| SMILES | CC(c1cc2nc(C)cc(N3CCCC(F)(F)C3)n2n1)c1ccc(cc1)C(F)(F)F |
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| Structure | 
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