| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50303848 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Opioid Receptor Binding Assay |
|---|
| Ki | 0.490±n/a nM |
|---|
| Citation |  Blumberg, LC; Deaver, DR; Eyerman, DJ; Wynn, TA Methods for treating depressive symptoms US Patent US10231963 Publication Date 3/19/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44789.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P35372 |
|---|
| Residue: | 400 |
|---|
| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
|
|
|
|---|
| BDBM50303848 |
|---|
| n/a |
|---|
| Name | BDBM50303848 |
|---|
| Synonyms: | (+)-trans-3-Methyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo-[4,5]furo[3,2-e]isoquinolin-9-ol | (-)-trans-3-Methyl-2,3,4,4aalpha,5,6,7,7aalpha-octahydro-1H-benzo-[4,5]furo[3,2-e]isoquinolin-9-ol | CHEMBL571843 | US10231963, Table B.12 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21NO2 |
|---|
| Mol. Mass. | 259.3434 |
|---|
| SMILES | CN1CC[C@]23[C@H](CCC[C@H]2C1)Oc1c3cccc1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
