| Reaction Details |
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 | Report a problem with these data |
| Target | Galectin-1 |
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| Ligand | BDBM21524 |
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| Substrate/Competitor | BDBM21520 |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 7.2±n/a |
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| Temperature | 297.15±n/a K |
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| Kd | 46000±n/a nM |
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| Citation |  Salameh, BA; Sundin, A; Leffler, H; Nilsson, UJ Thioureido N-acetyllactosamine derivatives as potent galectin-7 and 9N inhibitors. Bioorg Med Chem14:1215-20 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Galectin-1 |
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| Name: | Galectin-1 |
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| Synonyms: | 14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12 |
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| Type: | beta galactoside-binding protein |
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| Mol. Mass.: | 14713.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09382 |
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| Residue: | 135 |
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| Sequence: | MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIV
CNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINY
MAADGDFKIKCVAFD
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| BDBM21524 |
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| BDBM21520 |
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| Name | BDBM21524 |
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| Synonyms: | N-[(2R,3R,4R,5S,6R)-5-{[(2S,3R,4S,5R,6R)-4-[(diethylcarbamothioyl)amino]-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-hydroxy-6-(hydroxymethyl)-2-methoxyoxan-3-yl]acetamide | Thioureido N-acetyllactosamine derivative, 8 |
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| Type | n/a |
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| Emp. Form. | C20H37N3O10S |
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| Mol. Mass. | 511.587 |
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| SMILES | CCN(CC)C(=S)N[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]2[C@H](O)[C@@H](NC(C)=O)[C@H](OC)O[C@@H]2CO)[C@@H]1O |
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| Structure | 
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