| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50192447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | 3H]-Spiperone Binding Assay |
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| Ki | 63.1±n/a nM |
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| Citation |  Cremonesi, S; Micheli, F; Semerano, T; Tarsi, L Dopamine D3 receptor antagonists US Patent US10239870 Publication Date 3/26/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D2(Short) | Dopamine D2 S receptor |
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| Type: | n/a |
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| Mol. Mass.: | 47370.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416-2 |
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| Residue: | 414 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNG
HAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPF
FITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
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| BDBM50192447 |
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| n/a |
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| Name | BDBM50192447 |
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| Synonyms: | CHEMBL3975989 | US10239870, Example 53 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H26F3N5OS |
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| Mol. Mass. | 477.546 |
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| SMILES | Cc1ncoc1-c1nnc(SCCCN2CC[C@@]3(C[C@@H]3c3ccccc3C(F)(F)F)C2)n1C |r| |
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| Structure | 
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