| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2b |
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| Ligand | BDBM375234 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Adenosine A2B Receptor Subtype Competition Radioligand Binding Assay |
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| Ki | 24.0±n/a nM |
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| Citation |  Castro-Palomino Laria, JC; Camacho Gómez, JA; Mendoza Lizaldez, A Derivatives of 2-aminopyridine as adenosine A2B receptor antagonists and ligands of the melatonin MT3 receptors US Patent US10253017 Publication Date 4/9/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2b |
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| Name: | Adenosine receptor A2b |
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| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36341.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 332 |
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| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
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| BDBM375234 |
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| n/a |
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| Name | BDBM375234 |
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| Synonyms: | 3-chloro-5-(3-fluoropyridin-4-yl)-6-(6-methoxypyridin-3-yl)pyridin-2-amine | US10253017, Example 36 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12ClFN4O |
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| Mol. Mass. | 330.744 |
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| SMILES | COc1ccc(cn1)-c1nc(N)cc(Cl)c1-c1ccnc(F)c1 |
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| Structure | 
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