| Reaction Details |
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 | Report a problem with these data |
| Target | L-lactate dehydrogenase B chain |
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| Ligand | BDBM23222 |
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| Substrate/Competitor | BDBM19473 |
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| Meas. Tech. | Lactate Dehydrogenase Inhibition Assay |
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| pH | 7±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 123000±20600 nM |
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| Citation |  Choi, SR; Pradhan, A; Hammond, NL; Chittiboyina, AG; Tekwani, BL; Avery, MA Design, synthesis, and biological evaluation of Plasmodium falciparum lactate dehydrogenase inhibitors. J Med Chem50:3841-50 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| L-lactate dehydrogenase B chain |
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| Name: | L-lactate dehydrogenase B chain |
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| Synonyms: | LDH-B | LDHB | LDHB_BOVIN | Lactate Dehydrogenase |
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| Type: | Oxidoreductase; homotetramer |
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| Mol. Mass.: | 36722.72 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Purified from bovine heart. |
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| Residue: | 334 |
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| Sequence: | MATLKEKLIAPVAEEETRIPNNKITVVGVGQVGMACAISILGKSLTDELALVDVLEDKLK
GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF
IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG
IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY
EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG
LTSVINQKLKDEEVAQLKKSADTLWGIQKDLKDL
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| BDBM23222 |
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| BDBM19473 |
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| Name | BDBM23222 |
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| Synonyms: | Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Acid | carbamoylformic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C2H3NO3 |
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| Mol. Mass. | 89.0501 |
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| SMILES | NC(=O)C(O)=O |
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| Structure | 
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