| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM377141 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| Ki | 505±n/a nM |
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| Citation |  Zablocki, JA; Elzein, EO; Palle, VP; Belardinelli, L 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists US Patent US Patent
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | AA2AR_CAVPO | ADENOSINE A2 | ADORA2A | Adenosine A2a receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44955.08 |
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| Organism: | GUINEA PIG |
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| Description: | ADENOSINE A2 0 GUINEA PIG::P46616 |
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| Residue: | 409 |
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| Sequence: | MSSSVYITVELVIAVLAILGNVLVCWAVWINSNLQNVTNYFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLTITIDRYIAIRIPLRYNGLVTCTRAKG
IIAICWVLSFAIGLTPMLGWNNCSQPKGDKNHSESCDEGQVTCLFEDVVPMNYMVYYNFF
AFVLVPLLLMLGIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHPAKSLAIIVGLFA
LCCLPLNIINCFTFFCPECDHAPPWLMYLTIILSHGNSVVNPLIYAYRIREFRQTFRKII
RSHILRRRELFKAGGTSARASAAHSPEGEQVSLRLNGHPPGVWANGSALRPEQRPNGYVL
GLVSGRSAQRSHGDASLSDVELLSHEHKGTCPESPSLEDPPAHGGAGVS
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| BDBM377141 |
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| n/a |
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| Name | BDBM377141 |
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| Synonyms: | (1-{9-[(4S,2R,3R,5R)-3,4-dihydroxy-5-(hydrozymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-N- ethylcarboxamide | USRE47351, Compound 19 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N8O5 |
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| Mol. Mass. | 404.3806 |
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| SMILES | CCNC(=O)c1cnn(c1)-c1nc(N)c2ncn(C3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1 |r| |
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| Structure | 
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