| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-1 adrenergic receptor |
|---|
| Ligand | BDBM25768 |
|---|
| Substrate/Competitor | BDBM25747 |
|---|
| Meas. Tech. | 3H-CGP 12177 Whole Cell Binding Assay |
|---|
| pH | 7.4±n/a |
|---|
| Temperature | 310.15±n/a K |
|---|
| Kd | 302±14 nM |
|---|
| Citation |  Baker, JG The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol144:317-22 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Beta-1 adrenergic receptor |
|---|
| Name: | Beta-1 adrenergic receptor |
|---|
| Synonyms: | ADRB1 | ADRB1R | ADRB1_HUMAN | B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 51338.40 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08588 |
|---|
| Residue: | 477 |
|---|
| Sequence: | MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
|
|
|
|---|
| BDBM25768 |
|---|
| BDBM25747 |
|---|
| Name | BDBM25768 |
|---|
| Synonyms: | 1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol | ICI 118,551 | ICI 118551 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H27NO2 |
|---|
| Mol. Mass. | 277.4018 |
|---|
| SMILES | CC(C)NC(C)C(O)COc1ccc(C)c2CCCc12 |
|---|
| Structure | 
|
|---|
Search and Browse
