| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM25759 |
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| Substrate/Competitor | BDBM25747 |
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| Meas. Tech. | 3H-CGP 12177 Whole Cell Binding Assay |
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| Kd | 5±n/a nM |
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| Citation |  Baker, JG The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol144:317-22 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM25759 |
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| BDBM25747 |
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| Name | BDBM25759 |
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| Synonyms: | CHEMBL723 | Carvedilol | Coreg | Dilatrend | Eucardic | [3-(9H-carbazol-4-yloxy)-2-hydroxypropyl][2-(2-methoxyphenoxy)ethyl]amine |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26N2O4 |
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| Mol. Mass. | 406.4742 |
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| SMILES | COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12 |
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| Structure | 
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