| Reaction Details |
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 | Report a problem with these data |
| Target | Proto-oncogene Wnt-1 |
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| Ligand | BDBM384017 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | The screening assay for Wnt activity |
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| IC50 | 6.00±n/a nM |
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| Citation |  KC, SK; Wallace, DM; Cao, J; Chiruta, C; Hood, J 2-(1H-indazol-3-yl)-3H-imidazo[4,5-B]pyridine and therapeutic uses thereof US Patent US10280166 Publication Date 5/7/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Proto-oncogene Wnt-1 |
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| Name: | Proto-oncogene Wnt-1 |
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| Synonyms: | INT1 | Proto-oncogene Int-1 homolog | WNT1 | WNT1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41006.01 |
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| Organism: | Homo sapiens (human) |
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| Description: | P04628 |
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| Residue: | 370 |
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| Sequence: | MGLWALLPGWVSATLLLALAALPAALAANSSGRWWGIVNVASSTNLLTDSKSLQLVLEPS
LQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRG
CRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLF
GREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLR
AVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCT
YSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNC
THTRVLHECL
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| BDBM384017 |
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| n/a |
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| Name | BDBM384017 |
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| Synonyms: | US10280166, Compound 304 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H23N7O2 |
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| Mol. Mass. | 477.5172 |
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| SMILES | CCCCC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4c(ccnc4[nH]3)-c3ccoc3)c2c1 |
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| Structure | 
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