| Reaction Details |
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 | Report a problem with these data |
| Target | RNA-directed RNA polymerase |
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| Ligand | BDBM384111 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Measurement of Interferon Production in Human PBMC |
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| EC50 | 1210±n/a nM |
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| Citation |  Bonfanti, J; Doublet, FM; Embrechts, W; Fortin, JM; McGowan, DC; Muller, P; Raboisson, PJ Purine derivatives for the treatment of viral infections US Patent US10280167 Publication Date 5/7/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| RNA-directed RNA polymerase |
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| Name: | RNA-directed RNA polymerase |
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| Synonyms: | Hepatitis C virus NS5B RNA-dependent RNA polymerase | NS5B protein |
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| Type: | Protein |
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| Mol. Mass.: | 25173.95 |
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| Organism: | Hepatitis C virus |
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| Description: | Q8JXU8 |
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| Residue: | 229 |
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| Sequence: | RTEEAIYQCCDLDPQARVAIRSLTERLYVGGPLTNSRGENCGYRRRASGVLTTSCGNTLT
CYIKAQAACRAAGRQDCTMLVCGDDLVVICESAGVQEDAASLRAFTEAMTRYSAPPGDPP
QPEYDLELITSCSSNVSVAHDGAGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIM
FAPTLWVRMIMLTHFFSVLIARDQLEQALDCEIYGACYSIEPLLPPIIQ
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| BDBM384111 |
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| n/a |
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| Name | BDBM384111 |
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| Synonyms: | US10280167, Example 57 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N8O4 |
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| Mol. Mass. | 396.3601 |
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| SMILES | COC(=O)COc1ccc(Cn2c3nc(nc(N)c3[nH]c2=O)-c2ncc[nH]2)cn1 |
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| Structure | 
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