| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM25896 |
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| Substrate/Competitor | BDBM10856 |
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| Meas. Tech. | CA Inhibition Assay |
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| Ki | 66±n/a nM |
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| Citation |  Temperini, C; Innocenti, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studies. Bioorg Med Chem Lett18:4282-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII |
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| Type: | Enzyme |
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| Mol. Mass.: | 29522.80 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Murine cloned isozyme |
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| Residue: | 262 |
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| Sequence: | MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKII
SNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELH
VVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNF
DPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAA
FLLSNHRPPQPLKGRRVRASFY
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| BDBM25896 |
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| BDBM10856 |
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| Name | BDBM25896 |
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| Synonyms: | EMD 486019 | [2-(cycloheptylmethyl)-1,1-dioxo--benzothiophen-6-yl] sulfamate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H21NO5S2 |
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| Mol. Mass. | 371.472 |
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| SMILES | NS(=O)(=O)Oc1ccc2C=C(CC3CCCCCC3)S(=O)(=O)c2c1 |t:9| |
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| Structure | 
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