Reaction Details |
| Report a problem with these data |
Target | Serine/threonine-protein kinase pim-1 |
---|
Ligand | BDBM26668 |
---|
Substrate/Competitor | S6 Peptide Substrate |
---|
Meas. Tech. | Kinase Inhibition Assay |
---|
pH | 7.6±n/a |
---|
Temperature | 303.15±n/a K |
---|
Ki | 11±n/a nM |
---|
Citation | Pierce, AC; Jacobs, M; Stuver-Moody, C Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase. J Med Chem51:1972-5 (2008) [PubMed] Article |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Serine/threonine-protein kinase pim-1 |
---|
Name: | Serine/threonine-protein kinase pim-1 |
Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
Type: | Protein |
Mol. Mass.: | 35681.82 |
Organism: | Homo sapiens (Human) |
Description: | P11309 |
Residue: | 313 |
Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
|
|
|
BDBM26668 |
---|
S6 Peptide Substrate |
---|
Name: | S6 Peptide Substrate |
Synonyms: | n/a |
Type: | Peptide |
Mol. Mass.: | 1118.34 |
Organism: | n/a |
Description: | n/a |
Residue: | 9 |
Sequence: | |