| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interleukin-6 |
|---|
| Ligand | BDBM76986 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | cytomteric bead array (CBA) assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 60±n/a nM |
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| Comments | extracted |
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| Citation |  Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent US9694015 Publication Date 7/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Interleukin-6 |
|---|
| Name: | Interleukin-6 |
|---|
| Synonyms: | B-cell stimulatory factor 2 | BSF-2 | CDF | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IFNB2 | IL-6 | IL6 | IL6_HUMAN | Interferon beta-2 |
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| Type: | n/a |
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| Mol. Mass.: | 23717.96 |
|---|
| Organism: | Homo sapiens (Human) |
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| Description: | P05231 |
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| Residue: | 212 |
|---|
| Sequence: | MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
|
|
|
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| BDBM76986 |
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| n/a |
|---|
| Name | BDBM76986 |
|---|
| Synonyms: | 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione | US11059801, Compound D-17 | US9694015, Compound A |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H14N4O3 |
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| Mol. Mass. | 286.286 |
|---|
| SMILES | Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O |
|---|
| Structure | 
|
|---|
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