| Reaction Details |
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 | Report a problem with these data |
| Target | Glyceraldehyde-3-phosphate dehydrogenase, cytosolic |
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| Ligand | BDBM76986 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cytomteric bead array (CBA) assay |
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| Temperature | 310.15±n/a K |
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| IC50 | >10000±n/a nM |
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| Comments | extracted |
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| Citation |  Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent US9694015 Publication Date 7/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Glyceraldehyde-3-phosphate dehydrogenase, cytosolic |
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| Name: | Glyceraldehyde-3-phosphate dehydrogenase, cytosolic |
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| Synonyms: | G3PC_LEIME | GAPC | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase cytosolic | Glyceraldehyde-3-phosphate dehydrogenase, cytosolic |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35645.40 |
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| Organism: | Leishmania mexicana |
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| Description: | ChEMBL_72768 |
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| Residue: | 331 |
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| Sequence: | MVKVGINGFGRIGRVVFRAAQMRPDIEIVGINDLLDAEYMAYSLKYDSTHGRFDGTVEVI
KGALVVNGKSIRVTSERDPANLKWDEIGVEVVVESTGLFLTQETAHKHIEAGARRVVMTG
PPKDDTPMFVMGVNHTTYKGQPIISNASCTTNCLAPLAKVVNEKYGIVEGLMTTVHATTA
TQKTVDGPSLKDWRGGRGASQNIIPSSTGAPKAVGKVYPALDGKLTGMAFRVPTPNVSVV
DLTVRLEKPATYKDICAAIKAAAEGEMKGILGYTDDEVVSSDFNGVALTSVFDVKAGISL
NDHFVKLVSWYDNETGYSHKVLDLILHTSAR
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|
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| BDBM76986 |
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| n/a |
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| Name | BDBM76986 |
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| Synonyms: | 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione | US11059801, Compound D-17 | US9694015, Compound A |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N4O3 |
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| Mol. Mass. | 286.286 |
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| SMILES | Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O |
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| Structure | 
|
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