| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interleukin-6 |
|---|
| Ligand | BDBM65456 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | cytomteric bead array (CBA) assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 59±n/a nM |
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| Comments | extracted |
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| Citation |  Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent US9694015 Publication Date 7/4/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Interleukin-6 |
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| Name: | Interleukin-6 |
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| Synonyms: | B-cell stimulatory factor 2 | BSF-2 | CDF | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IFNB2 | IL-6 | IL6 | IL6_HUMAN | Interferon beta-2 |
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| Type: | n/a |
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| Mol. Mass.: | 23717.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05231 |
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| Residue: | 212 |
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| Sequence: | MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
|
|
|
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| BDBM65456 |
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| n/a |
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| Name | BDBM65456 |
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| Synonyms: | 19171-19-8 | 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | Actimid | CC-4047 | Pomalyst | US11059801, Compound D-4 | US20230271966, Compound Pomalidomide | US9694015, 6.2 | pomalidomide |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C13H11N3O4 |
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| Mol. Mass. | 273.2441 |
|---|
| SMILES | Nc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 |
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| Structure | 
|
|---|
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