| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-tyrosine kinase 6 |
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| Ligand | BDBM50184781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Screening Assay |
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| IC50 | 55.0±n/a nM |
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| Citation |  Unciti-Broceta, A; Fraser, C; O. Carragher, N Compounds US Patent US10294227 Publication Date 5/21/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein-tyrosine kinase 6 |
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| Name: | Protein-tyrosine kinase 6 |
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| Synonyms: | BRK | Breast tumor kinase | KH domain-containing, RNA-binding, signal transduction-associated protein 1 | PTK6 | PTK6_HUMAN | Protein-tyrosine kinase 6 (BRK) | Tyrosine Kinase BRK | Tyrosine-protein kinase 6 | Tyrosine-protein kinase BRK |
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| Type: | Tyrosine-protein kinase |
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| Mol. Mass.: | 51839.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 451 |
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| Sequence: | MVSRDQAHLGPKYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQG
YVPHNYLAERETVESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRD
TQAVRHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRAQSLSHGLRLAAPCRKHEPEPLPH
WDDWERPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRDNLLHQQMLQSEIQAMK
KLRHKHILALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGM
CYLESQNYIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSHDHNIPYKWTAPEALS
RGHYSTKSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLM
LTCWCRDPEQRPCFKALRERLSSFTSYENPT
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| BDBM50184781 |
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| n/a |
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| Name | BDBM50184781 |
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| Synonyms: | CHEMBL3823543 | US10294227, Code 533 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N8O |
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| Mol. Mass. | 500.6384 |
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| SMILES | COc1cc(ccc1NCc1ccccc1)-c1nn(CCN2CCC(CC2)N(C)C)c2ncnc(N)c12 |
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| Structure | 
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