| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein kinase HCK |
|---|
| Ligand | BDBM50184781 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Kinase Screening Assay |
|---|
| IC50 | <10.00±n/a nM |
|---|
| Citation |  Unciti-Broceta, A; Fraser, C; O. Carragher, N Compounds US Patent US10294227 Publication Date 5/21/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tyrosine-protein kinase HCK |
|---|
| Name: | Tyrosine-protein kinase HCK |
|---|
| Synonyms: | HCK | HCK_HUMAN | Hematopoietic cell kinase | Hemopoietic cell kinase | p59-HCK/p60-HCK | p59Hck | p61Hck |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 59600.18 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08631 |
|---|
| Residue: | 526 |
|---|
| Sequence: | MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIK
PGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSL
ATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSY
SLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVP
CMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVE
AFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLID
FSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFP
IKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPE
NCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
|
|
|
|---|
| BDBM50184781 |
|---|
| n/a |
|---|
| Name | BDBM50184781 |
|---|
| Synonyms: | CHEMBL3823543 | US10294227, Code 533 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H36N8O |
|---|
| Mol. Mass. | 500.6384 |
|---|
| SMILES | COc1cc(ccc1NCc1ccccc1)-c1nn(CCN2CCC(CC2)N(C)C)c2ncnc(N)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
