| Reaction Details |
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 | Report a problem with these data |
| Target | E3 ubiquitin-protein ligase XIAP [241-356] |
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| Ligand | BDBM391807 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biological Assays |
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| Ki | 37500±n/a nM |
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| Citation |  Pache, L; Chanda, SK; Vamos, MD; Cosford, ND; Teriete, P; Marlett, J; Diaz, A; Young, JA Use of inhibitor of apoptosis protein (IAP) antagonists in HIV therapy US Patent US10300074 Publication Date 5/28/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| E3 ubiquitin-protein ligase XIAP [241-356] |
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| Name: | E3 ubiquitin-protein ligase XIAP [241-356] |
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| Synonyms: | API3 | BIR3 (aa 241-356) | BIR3 domain | BIRC4 | IAP3 | XIAP | XIAP Bir3 | XIAP_HUMAN | amino acids 241-356 of XIAP |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 14548.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P98170[241-356] |
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| Residue: | 125 |
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| Sequence: | MRHHHHHHRSDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYA
LGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEEC
LVRTT
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| BDBM391807 |
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| n/a |
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| Name | BDBM391807 |
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| Synonyms: | US10300074, Compd 3 | US10300074, Compd 4 | US10300074, Compd 7 | US11111270, Compound 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H26N4O5 |
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| Mol. Mass. | 390.4335 |
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| SMILES | CN[C@@H](C)C(=O)N[C@H]1CO[C@H]2CCC(N2C1=O)C(=O)Nc1ccc(OC)cc1 |r| |
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| Structure | 
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