| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen-related receptor gamma |
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| Ligand | BDBM29608 |
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| Substrate/Competitor | BDBM20608 |
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| Meas. Tech. | Radioligand Displacement Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 13.1±2.34 nM |
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| Citation |  Matsushima, A; Teramoto, T; Okada, H; Liu, X; Tokunaga, T; Kakuta, Y; Shimohigashi, Y ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner. Biochem Biophys Res Commun373:408-13 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Estrogen-related receptor gamma |
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| Name: | Estrogen-related receptor gamma |
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| Synonyms: | ERR gamma-2 | ERR3 | ERR3_HUMAN | ERRG2 | ESRRG | Estrogen receptor-related protein 3 | Estrogen-Related Receptor, gamma | Estrogen-related receptor gamma | KIAA0832 | NR3B3 | Nuclear receptor subfamily 3 group B member 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51305.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1501351 |
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| Residue: | 458 |
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| Sequence: | MDSVELCLPESFSLHYEEELLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGG
SSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYML
NSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSC
QACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSH
LLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSL
LQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMK
LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT
LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV
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| BDBM29608 |
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| BDBM20608 |
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| Name | BDBM29608 |
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| Synonyms: | Bisphenol A (BPA) | Diphenylolpropane | US9688816, L |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16O2 |
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| Mol. Mass. | 228.2863 |
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| SMILES | CC(C)(c1ccc(O)cc1)c1ccc(O)cc1 |
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| Structure | 
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