| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, germ cell type |
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| Ligand | BDBM396265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Alkaline Phosphatase Assay |
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| EC50 | <20±n/a nM |
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| Citation |  Castro, AC; Grogan, MJ; McGovern, KJ; Tremblay, MR Methods of use of cyclopamine analogs US Patent US10314827 Publication Date 6/11/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Alkaline phosphatase, germ cell type |
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| Name: | Alkaline phosphatase, germ cell type |
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| Synonyms: | ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57374.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_29964 |
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| Residue: | 532 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLG
DGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLC
GVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYA
HTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDY
SQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRD
STLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERA
GQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVL
KDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHV
MAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
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| BDBM396265 |
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| n/a |
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| Name | BDBM396265 |
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| Synonyms: | US10314827, Compound 1 | US10314827, Compound 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H43NO2 |
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| Mol. Mass. | 425.6465 |
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| SMILES | C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC2=C(C)C1 |r,t:32| |
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| Structure | 
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