Reaction Details |
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Target | Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL) |
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Ligand | BDBM32281 |
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Substrate/Competitor | F-Bim |
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Meas. Tech. | Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. |
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pH | 7.4±n/a |
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Temperature | 277.15±n/a K |
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EC50 | 2850±0 nM |
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Citation | PubChem, PC Multiplexed dose response screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL. PubChem Bioassay(2008)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL) |
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Name: | Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL) |
Synonyms: | B-cell lymphoma-extra large protein (Bcl-xL) | B2CL1_HUMAN | BCL-xL | BCL2L | BCL2L1 | BCLX | Bcl-2-like protein 1 (Bcl-xL) | Isoform Bcl-X(L) |
Type: | Homodimers/heterodimers with BAX, BAK and BCL2 |
Mol. Mass.: | 26053.63 |
Organism: | Homo sapiens (Human) |
Description: | gi_510901 |
Residue: | 233 |
Sequence: | MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLA
DSPAVNGATAHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY
QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP
WIQENGGWDTFVELYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
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BDBM32281 |
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F-Bim |
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Name: | F-Bim |
Synonyms: | n/a |
Type: | fluorescent peptide probe |
Mol. Mass.: | 3923.40 |
Organism: | n/a |
Description: | n/a |
Residue: | 32 |
Sequence: | FITC-Ahx-DMRPEIWIAQELRRIGDEFNAYYAR-OH
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