| Reaction Details |
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 | Report a problem with these data |
| Target | Sortase A |
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| Ligand | BDBM33312 |
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| Substrate/Competitor | BDBM33299 |
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| Meas. Tech. | Fluorescence Resonance Energy Transfer (FRET) Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 27000±9000 nM |
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| Citation |  Suree, N; Yi, SW; Thieu, W; Marohn, M; Damoiseaux, R; Chan, A; Jung, ME; Clubb, RT Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors. Bioorg Med Chem17:7174-85 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Inhibition_Run data, Solution Info, Assay Method |
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| Sortase A |
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| Name: | Sortase A |
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| Synonyms: | LPXTG-site transpeptidase family protein | SRTA_BACAN | Sortase A (SrtA) | srtA |
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| Type: | Enzyme |
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| Mol. Mass.: | 23150.63 |
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| Organism: | Bacillus anthracis |
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| Description: | A0A0E0VVI0 |
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| Residue: | 210 |
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| Sequence: | MNKQRIYSIVAILLFVVGGVLIGKPFYDGYQAEKKQTENVQAVQKMDYEKHETEFVDASK
IDQPDLAEVANASLDKKQVIGRISIPSVSLELPVLKSSTEKNLLSGAATVKENQVMGKGN
YALAGHNMSKKGVLFSDIASLKKGDKIYLYDNENEYEYAVTGVSEVTPDKWEVVEDHGKD
EITLITCVSVKDNSKRYVVAGDLVGTKAKK
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| BDBM33312 |
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| BDBM33299 |
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| Name | BDBM33312 |
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| Synonyms: | rhodanine, 1-13 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13NO2S2 |
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| Mol. Mass. | 327.421 |
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| SMILES | C=CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccccc2)C1=O |
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| Structure | 
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