| Reaction Details |
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 | Report a problem with these data |
| Target | Sortase A |
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| Ligand | BDBM33371 |
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| Substrate/Competitor | BDBM33299 |
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| Meas. Tech. | Fluorescence Resonance Energy Transfer (FRET) Assay |
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| IC50 | 1400±n/a nM |
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| Citation |  Suree, N; Yi, SW; Thieu, W; Marohn, M; Damoiseaux, R; Chan, A; Jung, ME; Clubb, RT Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors. Bioorg Med Chem17:7174-85 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sortase A |
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| Name: | Sortase A |
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| Synonyms: | LPXTG-site transpeptidase family protein | SRTA_BACAN | Sortase A (SrtA) | srtA |
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| Type: | Enzyme |
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| Mol. Mass.: | 23150.63 |
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| Organism: | Bacillus anthracis |
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| Description: | A0A0E0VVI0 |
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| Residue: | 210 |
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| Sequence: | MNKQRIYSIVAILLFVVGGVLIGKPFYDGYQAEKKQTENVQAVQKMDYEKHETEFVDASK
IDQPDLAEVANASLDKKQVIGRISIPSVSLELPVLKSSTEKNLLSGAATVKENQVMGKGN
YALAGHNMSKKGVLFSDIASLKKGDKIYLYDNENEYEYAVTGVSEVTPDKWEVVEDHGKD
EITLITCVSVKDNSKRYVVAGDLVGTKAKK
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| BDBM33371 |
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| BDBM33299 |
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| Name | BDBM33371 |
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| Synonyms: | pyrazolethione, 3-9 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19N5S |
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| Mol. Mass. | 397.495 |
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| SMILES | Cc1[nH]n(-c2ccccc2)c(=S)c1C=Nc1ccc(cc1)N=Nc1ccccc1 |w:13.14,21.23| |
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| Structure | 
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