| Reaction Details |
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 | Report a problem with these data |
| Target | Prothrombin |
|---|
| Ligand | BDBM32881 |
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| Substrate/Competitor | Boc-Val-Pro-Arg-AMC |
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| Meas. Tech. | Thrombin 1536 HTS Dose Response Confirmation |
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| pH | 7.5±n/a |
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| Temperature | 296.15±n/a K |
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| IC50 | 1±n/a nM |
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| Citation |  PubChem, PC Thrombin 1536 HTS Dose Response Confirmation PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Prothrombin |
|---|
| Name: | Prothrombin |
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| Synonyms: | Activation peptide fragment 1 | Activation peptide fragment 2 | Coagulation factor II | F2 | Prothrombin precursor | THRB_HUMAN | Thrombin heavy chain | Thrombin light chain |
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| Type: | Protein |
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| Mol. Mass.: | 70029.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00734 |
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| Residue: | 622 |
|---|
| Sequence: | MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLEREC
VEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHV
NITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQE
CSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASA
QAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETG
DGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYI
DGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTEN
DLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHP
VCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDST
RIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY
GFYTHVFRLKKWIQKVIDQFGE
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|
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| BDBM32881 |
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| Boc-Val-Pro-Arg-AMC |
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| Name: | Boc-Val-Pro-Arg-AMC |
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| Synonyms: | n/a |
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| Type: | fluorogenic substrate |
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| Mol. Mass.: | 358.43 |
|---|
| Organism: | n/a |
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| Description: | n/a |
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| Residue: | 3 |
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| Sequence: | |
|---|
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