| Reaction Details |
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 | Report a problem with these data |
| Target | Matrix metalloproteinase-17 |
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| Ligand | BDBM400231 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | >100000±n/a nM |
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| Citation |  Kamei, N; Sumikawa, Y; Kamimura, D; Todo, S; Yamada, T; Tokuoka, S Pyridone derivative, pharmaceutical containing the same and methods of use thereof US Patent US10000476 Publication Date 6/19/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrix metalloproteinase-17 |
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| Name: | Matrix metalloproteinase-17 |
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| Synonyms: | MMP-17 | MMP17 | MMP17_HUMAN | MT-MMP 4 | MT4-MMP | MT4MMP | MTMMP4 | Matrix metalloproteinase 17 | Matrix metalloproteinase-17 | Membrane-type matrix metalloproteinase 4 | Membrane-type-4 matrix metalloproteinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66652.56 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1433225 |
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| Residue: | 603 |
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| Sequence: | MRRRAARGPGPPPPGPGLSRLPLPLLLLLALGTRGGCAAPAPAPRAEDLSLGVEWLSRFG
YLPPADPTTGQLQTQEELSKAITAMQQFGGLEATGILDEATLALMKTPRCSLPDLPVLTQ
ARRRRQAPAPTKWNKRNLSWRVRTFPRDSPLGHDTVRALMYYALKVWSDIAPLNFHEVAG
SAADIQIDFSKADHNDGYPFDGPGGTVAHAFFPGHHHTAGDTHFDDDEAWTFRSSDAHGM
DLFAVAVHEFGHAIGLSHVAAAHSIMRPYYQGPVGDPLRYGLPYEDKVRVWQLYGVRESV
SPTAQPEEPPLLPEPPDNRSSAPPRKDVPHRCSTHFDAVAQIRGEAFFFKGKYFWRLTRD
RHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRP
VSDFSLPPGGIDAAFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYPAQSPLWRGVPSTLD
DAMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTARDWLVCGDSQADGSVAAGVDAAE
GPRAPPGQHDQSRSEDGYEVCSCTSGASSPPGAPGPLVAATMLLLLPPLSPGALWTAAQA
LTL
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| BDBM400231 |
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| n/a |
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| Name | BDBM400231 |
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| Synonyms: | US10000476, Compound I-1 | US10000476, Compound I-55 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O3 |
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| Mol. Mass. | 298.2967 |
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| SMILES | Cc1cccn(CC2(NC(=O)NC2=O)c2ccncc2)c1=O |
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| Structure | 
|
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