| Reaction Details |
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 | Report a problem with these data |
| Target | Uracil-DNA glycosylase |
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| Ligand | BDBM36455 |
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| Substrate/Competitor | BDBM36458 |
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| Meas. Tech. | UNG Inhibition Assay |
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| pH | 8±0 |
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| IC50 | 3.15e+5±n/a nM |
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| Citation |  Chung, S; Parker, JB; Bianchet, M; Amzel, LM; Stivers, JT Impact of linker strain and flexibility in the design of a fragment-based inhibitor. Nat Chem Biol5:407-13 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Uracil-DNA glycosylase |
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| Name: | Uracil-DNA glycosylase |
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| Synonyms: | DGU | UDG | UNG | UNG1 | UNG15 | UNG_HUMAN | Uracil-DNA glycosylase (UNG) |
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| Type: | Protein |
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| Mol. Mass.: | 34661.15 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P1305 |
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| Residue: | 313 |
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| Sequence: | MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGT
PPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAE
ERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLE
NIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVS
WLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELL
QKSGKKPIDWKEL
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| BDBM36455 |
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| BDBM36458 |
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| Name | BDBM36455 |
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| Synonyms: | 6-[4-[(3-Carboxybenzylamino)butylamino]methyl]uracil, 27 | CID25210542 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H22N4O4 |
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| Mol. Mass. | 346.381 |
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| SMILES | OC(=O)c1cccc(CNCCCCNCc2cc(=O)[nH]c(=O)[nH]2)c1 |
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| Structure | 
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