| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled estrogen receptor 1 |
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| Ligand | BDBM36490 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Binding Assay |
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| Ki | 25±0.0 nM |
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| Citation |  Revankar, CM; Mitchell, HD; Field, AS; Burai, R; Corona, C; Ramesh, C; Sklar, LA; Arterburn, JB; Prossnitz, ER Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30. ACS Chem Biol2:536-44 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled estrogen receptor 1 |
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| Name: | G-protein coupled estrogen receptor 1 |
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| Synonyms: | CEPR | CMKRL2 | DRY12 | G-protein coupled estrogen receptor 1 | G-protein-coupled receptor (GPR30 ) | GPER | GPER1 | GPER1_HUMAN | GPR30 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42259.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_982507 |
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| Residue: | 375 |
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| Sequence: | MDVTSQARGVGLEMYPGTAQPAAPNTTSPELNLSHPLLGTALANGTGELSEHQQYVIGLF
LSCLYTIFLFPIGFVGNILILVVNISFREKMTIPDLYFINLAVADLILVADSLIEVFNLH
ERYYDIAVLCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGL
IWMASVSATLVPFTAVHLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSLIVRV
LVRAHRHRGLRPRRQKALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQSFRH
AHPLTGHIVNLAAFSNSCLNPLIYSFLGETFRDKLRLYIEQKTNLPALNRFCHAALKAVI
PDSTEQSDVRFSSAV
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| BDBM36490 |
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| n/a |
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| Name | BDBM36490 |
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| Synonyms: | E2-NH3+ |
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| Type | Small organic molecule |
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| Emp. Form. | C27H32NO2 |
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| Mol. Mass. | 402.5479 |
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| SMILES | C[C@]12CCC3C(CCc4cc(O)ccc34)C1CC[C@@]2(O)C#Cc1ccc(C[NH3+])cc1 |r| |
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| Structure | 
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