| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vitamin D-binding protein |
|---|
| Ligand | BDBM36717 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | DBP Binding Assay |
|---|
| pH | 7.4±0 |
|---|
| Temperature | 277.15±0 K |
|---|
| IC50 | 40±0.0 nM |
|---|
| Citation |  Boehm, MF; Fitzgerald, P; Zou, A; Elgort, MG; Bischoff, ED; Mere, L; Mais, DE; Bissonnette, RP; Heyman, RA; Nadzan, AM; Reichman, M; Allegretto, EA Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3. Chem Biol6:265-75 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Vitamin D-binding protein |
|---|
| Name: | Vitamin D-binding protein |
|---|
| Synonyms: | Dbp | Gc | Gc-globulin | Group-specific component | VDB | VTDB_RAT |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 53539.97 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | EBI_10076 |
|---|
| Residue: | 476 |
|---|
| Sequence: | MKRVLVLLLALAFGHALERGRDYEKDKVCQELSTLGKDDFRSLSLILYSRKFPSSTFEQV
SQLVKEVVSLTEECCAEGADPNCYDTRTSELSIKSCESDAPFPVHPGTSECCTKEGLERK
LCMAALSHQPQEFPAYVEPTNDEICEAFRKDPKGFADQFLFEYSSNYGQAPLPLLVGYTK
SYLSMVGSCCTSAKPTVCFLKERLQMKQLLLLTTMSNRVCSQYAAYGKEKSRMSHLIKLA
QKVPTANLEDVLPLAEDLTEILSRCCKSTSEDCMARELPEHTLKICGNLSKKNSKFEECC
YETTPMGIFMCSYFMPTAEPLQLPAIKLPTSKDLCGQSATQAMDQYTFELSRRTQVPEVF
LSKVLDTTLKTLRECCDTQDSVSCFSTQSPLMKRQLTSFIEKGQEMCADYSENTFTEYKK
KLAERLRTKMPNASPEELADMVAKHSDFASKCCSINSPPRYCSSQIDAEMRDILQS
|
|
|
|---|
| BDBM36717 |
|---|
| n/a |
|---|
| Name | BDBM36717 |
|---|
| Synonyms: | 1,25(OH)2D3 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H50O |
|---|
| Mol. Mass. | 426.7174 |
|---|
| SMILES | CC(CCCC(C)(C)O)C1CCC2CC(CCC12C)\C=C\C=C1\C[C@@H](C)C[C@H](C)C1=C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
