| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase Lyn |
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| Ligand | BDBM264397 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assays |
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| IC50 | <100.0±n/a nM |
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| Citation |  Zeng, Q; Faris, M; Mollard, A; Warner, SL; Flynn, GA Multiple kinase pathway inhibitors US Patent US9714247 Publication Date 7/25/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase Lyn |
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| Name: | Tyrosine-protein kinase Lyn |
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| Synonyms: | JTK8 | LYN | LYN_HUMAN | Lck/Yes-related novel protein tyrosine kinase | Tyrosine-protein kinase Lyn (LYN) | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog | p53Lyn | p56Lyn |
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| Type: | Protein |
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| Mol. Mass.: | 58575.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07948 |
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| Residue: | 512 |
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| Sequence: | MGCIKSKGKDSLSDDGVDLKTQPVRNTERTIYVRDPTSNKQQRPVPESQLLPGQRFQTKD
PEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAK
LNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVI
KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPWDKDAW
EIPRESIKLVKRLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHD
KLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIER
KNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCF
TIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVENCPDELYDIMKMCW
KEKAEERPTFDYLQSVLDDFYTATEGQYQQQP
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| BDBM264397 |
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| n/a |
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| Name | BDBM264397 |
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| Synonyms: | US9714247, 119 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H33FN6O2 |
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| Mol. Mass. | 516.6097 |
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| SMILES | CCn1c2cc(Nc3ccc(cn3)N(C)C3CCN(C)CC3)ncc2cc(-c2cc(OC)ccc2F)c1=O |
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| Structure | 
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