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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase Lyn | ||
| Ligand | BDBM264412 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assays | ||
| IC50 | <100.0±n/a nM | ||
| Citation |  Zeng, Q; Faris, M; Mollard, A; Warner, SL; Flynn, GA Multiple kinase pathway inhibitors US Patent US9714247 Publication Date 7/25/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase Lyn | |||
| Name: | Tyrosine-protein kinase Lyn | ||
| Synonyms: | JTK8 | LYN | LYN_HUMAN | Lck/Yes-related novel protein tyrosine kinase | Tyrosine-protein kinase Lyn (LYN) | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog | p53Lyn | p56Lyn | ||
| Type: | Protein | ||
| Mol. Mass.: | 58575.92 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P07948 | ||
| Residue: | 512 | ||
| Sequence: |
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| BDBM264412 | |||
| n/a | |||
| Name | BDBM264412 | ||
| Synonyms: | US9714247, 134 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H25F3N6O | ||
| Mol. Mass. | 494.5115 | ||
| SMILES | CN1CCN(CCn2c3cc(Nc4ccc(F)cn4)ncc3cc(-c3c(F)cccc3F)c2=O)CC1 |(4,-6.93,;4,-5.39,;2.67,-4.62,;2.67,-3.08,;4,-2.31,;4,-.77,;2.67,,;2.67,1.54,;1.33,2.31,;,1.54,;-1.33,2.31,;-2.67,1.54,;-4,2.31,;-4,3.85,;-5.33,4.62,;-6.67,3.85,;-8,4.62,;-6.67,2.31,;-5.33,1.54,;-1.33,3.85,;,4.62,;1.33,3.85,;2.67,4.62,;4,3.85,;5.33,4.62,;6.67,3.85,;6.67,2.31,;8,4.62,;8,6.16,;6.67,6.93,;5.33,6.16,;4,6.93,;4,2.31,;5.33,1.54,;5.33,-3.08,;5.33,-4.62,)| | ||
| Structure | 
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