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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Proto-oncogene tyrosine-protein kinase Src | ||
| Ligand | BDBM264417 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assays | ||
| IC50 | <100.0±n/a nM | ||
| Citation |  Zeng, Q; Faris, M; Mollard, A; Warner, SL; Flynn, GA Multiple kinase pathway inhibitors US Patent US9714247 Publication Date 7/25/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Proto-oncogene tyrosine-protein kinase Src | |||
| Name: | Proto-oncogene tyrosine-protein kinase Src | ||
| Synonyms: | Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src | ||
| Type: | Protein | ||
| Mol. Mass.: | 59838.60 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P12931 | ||
| Residue: | 536 | ||
| Sequence: |
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| BDBM264417 | |||
| n/a | |||
| Name | BDBM264417 | ||
| Synonyms: | US9714247, 139 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H34F2N6O | ||
| Mol. Mass. | 544.6381 | ||
| SMILES | CN(C1CCN(C)CC1)c1ccc(Nc2cc3n(C4CCCC4)c(=O)c(cc3cn2)-c2c(F)cccc2F)nc1 |(-5.33,3.88,;-5.33,2.34,;-6.67,1.57,;-6.67,.03,;-8,-.74,;-9.34,.03,;-10.67,-.74,;-9.34,1.57,;-8,2.34,;-4,1.57,;-2.67,2.34,;-1.33,1.57,;-1.33,.03,;,-.74,;1.33,.03,;2.67,-.74,;4,.03,;5.33,-.74,;5.33,-2.28,;4.09,-3.19,;4.56,-4.65,;6.1,-4.65,;6.58,-3.19,;6.67,.03,;8,-.74,;6.67,1.57,;5.33,2.34,;4,1.57,;2.67,2.34,;1.33,1.57,;8,2.34,;9.34,1.57,;9.34,.03,;10.67,2.34,;10.67,3.88,;9.34,4.65,;8,3.88,;6.67,4.65,;-2.67,-.74,;-4,.03,)| | ||
| Structure | 
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