Reaction Details | |||
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Target | Proto-oncogene tyrosine-protein kinase Src | ||
Ligand | BDBM264418 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Assays | ||
IC50 | <100.0±n/a nM | ||
Citation | Zeng, Q; Faris, M; Mollard, A; Warner, SL; Flynn, GA Multiple kinase pathway inhibitors US Patent US9714247 Publication Date 7/25/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
Proto-oncogene tyrosine-protein kinase Src | |||
Name: | Proto-oncogene tyrosine-protein kinase Src | ||
Synonyms: | Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src | ||
Type: | Protein | ||
Mol. Mass.: | 59838.60 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P12931 | ||
Residue: | 536 | ||
Sequence: |
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BDBM264418 | |||
n/a | |||
Name | BDBM264418 | ||
Synonyms: | US9714247, 140 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H26F2N6O | ||
Mol. Mass. | 476.521 | ||
SMILES | CN(C1CCN(C)CC1)c1ccc(Nc2cc3[nH]c(=O)c(cc3cn2)-c2c(F)cccc2F)nc1 |(-5.33,1.93,;-5.33,.38,;-6.67,-.38,;-6.67,-1.93,;-8,-2.69,;-9.34,-1.93,;-10.67,-2.69,;-9.34,-.38,;-8,.38,;-4,-.38,;-2.67,.38,;-1.33,-.38,;-1.33,-1.93,;,-2.69,;1.33,-1.93,;2.67,-2.69,;4,-1.93,;5.33,-2.69,;6.67,-1.93,;8,-2.69,;6.67,-.38,;5.33,.38,;4,-.38,;2.67,.38,;1.33,-.38,;8,.38,;9.34,-.38,;9.34,-1.93,;10.67,.38,;10.67,1.93,;9.34,2.69,;8,1.93,;6.67,2.69,;-2.67,-2.69,;-4,-1.93,)| | ||
Structure |