| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM36830 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR |
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| EC50 | 4292±n/a nM |
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| Citation |  PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42836.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21453 |
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| Residue: | 382 |
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| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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| BDBM36830 |
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| n/a |
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| Name | BDBM36830 |
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| Synonyms: | 2-[3-keto-6-[(2-methoxyphenyl)carbamoyl]-2,2-dimethyl-1,4-benzoxazin-4-yl]acetic acid ethyl ester | 2-[6-[(2-methoxyanilino)-oxomethyl]-2,2-dimethyl-3-oxo-1,4-benzoxazin-4-yl]acetic acid ethyl ester | MLS000068354 | SMR000006960 | [6-(2-Methoxy-phenylcarbamoyl)-2,2-dimethyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl]-acetic acid ethyl ester | cid_646770 | ethyl 2-[6-[(2-methoxyphenyl)carbamoyl]-2,2-dimethyl-3-oxidanylidene-1,4-benzoxazin-4-yl]ethanoate | ethyl 2-[6-[(2-methoxyphenyl)carbamoyl]-2,2-dimethyl-3-oxo-1,4-benzoxazin-4-yl]acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24N2O6 |
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| Mol. Mass. | 412.4358 |
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| SMILES | CCOC(=O)CN1C(=O)C(C)(C)Oc2ccc(cc12)C(=O)Nc1ccccc1OC |
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| Structure | 
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