| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM37271 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR |
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| EC50 | 13380±n/a nM |
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| Citation |  PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42836.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21453 |
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| Residue: | 382 |
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| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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| BDBM37271 |
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| n/a |
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| Name | BDBM37271 |
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| Synonyms: | 1-(2-methylpropyl)-2-oxidanyl-4-oxidanylidene-N-(2-sulfamoylphenyl)quinoline-3-carboxamide | 2-hydroxy-1-(2-methylpropyl)-4-oxo-N-(2-sulfamoylphenyl)-3-quinolinecarboxamide | 2-hydroxy-1-(2-methylpropyl)-4-oxo-N-(2-sulfamoylphenyl)quinoline-3-carboxamide | 2-hydroxy-1-isobutyl-4-keto-N-(2-sulfamoylphenyl)quinoline-3-carboxamide | CHEMBL197014 | MLS000106809 | SMR000111185 | cid_1370032 | cid_54676686 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O5S |
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| Mol. Mass. | 415.463 |
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| SMILES | CC(C)Cn1c2ccccc2c(O)c(C(=O)Nc2ccccc2S(N)(=O)=O)c1=O |
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| Structure | 
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