| Reaction Details |
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 | Report a problem with these data |
| Target | Diphosphomevalonate decarboxylase |
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| Ligand | BDBM34233 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response |
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| IC50 | 513.1±n/a nM |
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| Citation |  PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay(2007)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Diphosphomevalonate decarboxylase |
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| Name: | Diphosphomevalonate decarboxylase |
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| Synonyms: | n/a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 35571.44 |
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| Organism: | Streptococcus pneumoniae D39 |
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| Description: | A0A0H2ZN59 |
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| Residue: | 317 |
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| Sequence: | MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEF
YINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNA
YFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKK
KPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATT
KTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQR
YRLIVSKTKDLSQDDCC
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|
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| BDBM34233 |
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| n/a |
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| Name | BDBM34233 |
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| Synonyms: | 2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen) | 2-phenyl-1,2-benzisoselazol-3(2H)-one | 2-phenyl-1,2-benzoselenazol-3-one | 2-phenylbenzo[d][1,2]selenazol-3(2H)-one | CHEMBL51085 | EBSELEN | Ebselen (C5) | MLS000028488 | SMR000058445 | cid_3194 | med.21724, Compound 153 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9NOSe |
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| Mol. Mass. | 274.18 |
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| SMILES | O=c1n([se]c2ccccc12)-c1ccccc1 |
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| Structure | 
|
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