Ki Summary

Reaction Details

Report a problem with these data

Target

Mevalonate kinase

Ligand

BDBM38517

Substrate/Competitor

n/a

Meas. Tech.

Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response

IC50

>9999000±n/a nM

Citation

PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay(2007)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Mevalonate kinase

Name:

Mevalonate kinase

Synonyms:

n/a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

31420.64

Organism:

Streptococcus pneumoniae D39

Description:

A0A0H2ZQX9

Residue:

292

Sequence:

MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMA
VYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILV
NRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQ
VVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLV
ETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL

BDBM38517

n/a

Name

BDBM38517

Synonyms:

4-[2-[4-(2-furoyl)piperazino]-2-keto-ethyl]-2-methyl-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester | 4-[2-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]-2-oxoethyl]-2-methyl-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl ester | 4-{2-[4-(Furan-2-carbonyl)-piperazin-1-yl]-2-oxo-ethyl}-2-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester | MLS000029962 | SMR000008315 | cid_646472 | ethyl 4-[2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl]-2-methylthieno[3,2-b]pyrrole-5-carboxylate | ethyl 4-[2-[4-(furan-2-ylcarbonyl)piperazin-1-yl]-2-oxidanylidene-ethyl]-2-methyl-thieno[3,2-b]pyrrole-5-carboxylate

Type

Small organic molecule

Emp. Form.

C21H23N3O5S

Mol. Mass.

429.489

SMILES

CCOC(=O)c1cc2sc(C)cc2n1CC(=O)N1CCN(CC1)C(=O)c1ccco1

Structure