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Reaction Details
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TargetMevalonate kinase
LigandBDBM38543
Substrate/Competitorn/a
Meas. Tech.Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50>9999000±n/a nM
Citation PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay(2007)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Mevalonate kinase
Name:Mevalonate kinase
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:31420.64
Organism:Streptococcus pneumoniae D39
Description:A0A0H2ZQX9
Residue:292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMA
VYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILV
NRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQ
VVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLV
ETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
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  Blast E-value cutoff:
BDBM38543
n/a
NameBDBM38543
Synonyms:2-(2-furoylamino)acetic acid [2-keto-2-(p-tolyl)ethyl] ester | 2-[[2-furanyl(oxo)methyl]amino]acetic acid [2-(4-methylphenyl)-2-oxoethyl] ester | MLS000035391 | SMR000015167 | [(Furan-2-carbonyl)-amino]-acetic acid 2-oxo-2-p-tolyl-ethyl ester | [2-(4-methylphenyl)-2-oxidanylidene-ethyl] 2-(furan-2-ylcarbonylamino)ethanoate | [2-(4-methylphenyl)-2-oxoethyl] 2-(furan-2-carbonylamino)acetate | cid_655320
TypeSmall organic molecule
Emp. Form.C16H15NO5
Mol. Mass.301.294
SMILESCc1ccc(cc1)C(=O)COC(=O)CNC(=O)c1ccco1
Structure
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