Reaction Details |
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Target | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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Ligand | BDBM38856 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) |
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IC50 | 948±n/a nM |
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Citation | PubChem, PC Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) PubChem Bioassay(2007)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
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Name: | Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) |
Synonyms: | NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA |
Type: | PROTEIN |
Mol. Mass.: | 63033.59 |
Organism: | Homo sapiens (Human) |
Description: | EBI_101591 |
Residue: | 556 |
Sequence: | MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCI
LSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGV
ITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGR
MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGH
TPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPT
VSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKI
TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYAS
PDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQ
KIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLY
KELFTSEFEPAMQIDG
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BDBM38856 |
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n/a |
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Name | BDBM38856 |
Synonyms: | 2,6-Dimethyl-benzo[1,2-b;4,5-b']difuran-3,7-dicarboxylic acid bis-(2-dimethylamino-ethyl) ester | 2,6-dimethylfuro[2,3-f]benzofuran-3,7-dicarboxylic acid bis[2-(dimethylamino)ethyl] ester | MLS000033569 | SMR000014222 | bis[2-(dimethylamino)ethyl] 2,6-dimethylfuro[2,3-f][1]benzofuran-3,7-dicarboxylate | cid_650137 |
Type | Small organic molecule |
Emp. Form. | C22H28N2O6 |
Mol. Mass. | 416.4675 |
SMILES | CN(C)CCOC(=O)c1c(C)oc2cc3c(C(=O)OCCN(C)C)c(C)oc3cc12 |
Structure |
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